Barbiturates
Interpretation
- If there is a question as to a patient's therapeutic compliance, a serum test request for the specific drug of interest may be of help.
Metabolites
- Mephobarbital is metabolized to phenobarbital.
Mephobarbital → Phenobarbital
Confirmation Tests:
Approximate Detection Times
| Barbiturates | LOQ (ng/mL) | Detection Time* up to |
|---|---|---|
| Long-Acting | ||
| Phenobarbital | 100 | 15 days |
| Intermediate-Acting | ||
| Butalbital | 100 | 7 days |
| Amobarbital | 100 | 3 days |
| Short-Acting | ||
| Pentobarbital | 100 | 3 days |
| Secobarbital | 100 | 3 days |
*These are approximate detection times for the drug or metabolites in urine. The actual detection time depends on dose, frequency of
use, and individual metabolism.